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Structure of 98027-63-5
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5-Sulfamoylfuran-2-carboxylic acid features a furan ring bearing a sulfamoyl group at the 5-position and a carboxylic acid at the 2-position, combining strong hydrogen-bonding capacity with moderate acidity. This dual functionality enables efficient integration into bioactive scaffolds, particularly in kinase inhibitor design and enzyme probe development. The molecule exhibits enhanced solubility in aqueous systems due to its polar substituents, supporting use in biological assays and medicinal chemistry campaigns under standard conditions.
5-Sulfamoylfuran-2-carboxylic acid serves as a versatile building block in medicinal chemistry, enabling the construction of bioactive heterocycles through established coupling and functionalization reactions. Its dual acidic functionality—carboxylic acid and sulfonamide—provides orthogonal reactivity for peptide coupling, amidation, and metal-mediated transformations. The molecule exhibits good bench stability and facilitates purification via standard chromatographic methods, making it well-suited for iterative synthesis campaigns targeting kinase inhibitors and other pharmacologically relevant scaffolds.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: