(R)-5-(Bromomethyl)pyrrolidin-2-one

Name: (R)-5-(Bromomethyl)pyrrolidin-2-one
Brand: ChemScene
Availability: InStock
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CAS No. 98612-60-3
Cat. No. CS-W020693
Purity≥97%
MDL No.MFCD06799465

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Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
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(R)-5-(Bromomethyl)pyrrolidin-2-one|CS-W020693

Structure of 98612-60-3

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Description

(R)-5-(Bromomethyl)pyrrolidin-2-one features a stereodefined pyrrolidinone core with a reactive bromomethyl handle at the 5-position. This bench-stable, moisture-tolerant reagent integrates readily into synthetic sequences requiring selective alkylation or chain extension. The chiral scaffold supports asymmetric synthesis and enables access to complex nitrogen-containing architectures.

Application

(R)-5-(Bromomethyl)pyrrolidin-2-one serves as a versatile chiral building block for the synthesis of bioactive heterocycles and medicinal chemistry intermediates. The bromomethyl group enables efficient nucleophilic substitution, while the pyrrolidinone scaffold offers excellent functional group tolerance and bench stability. Its stereochemical integrity supports reliable incorporation into complex molecular architectures via standard coupling protocols.

General Information

CAS No. 98612-60-3
Cat. No. CS-W020693
Purity ≥97%
MDL No. MFCD06799465
Storage Store at room temperature
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₅H₈BrNO
Molecular Weight 178.03
Synonym(s) (R)-5-Bromomethyl-2-pyrrolidinone
SMILES O=C1N[C@@H](CBr)CC1

Computational Chemistry Data

TPSA 29.1
LogP 0.6599
H_Acceptors 1
H_Donors 1
Rotatable_Bonds 1

Safety Information

Download SDS

GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H302-H317-H319
Precautionary Statements : P261-P264-P270-P272-P280-P302+P352-P330-P362+P364-P501

Quality Control

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Other Classifications

Building Blocks Skeleton Aliphatic heterocycle compounds Pyrrolidine compounds

Building Blocks Skeleton Chiral compounds Chiral Building Blocks

Key Words

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(R)-5-(Bromomethyl)pyrrolidin-2-one

CAS No. 98612-60-3

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