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Structure of 98626-92-7
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2-Bromo-6-(methylsulfonyl)pyridine features a bromine atom at the 2-position and a methylsulfonyl group at the 6-position on a pyridine ring, enabling efficient cross-coupling reactions. The electron-withdrawing sulfone moiety enhances reactivity in palladium-catalyzed transformations while maintaining bench stability. This compound serves as a key intermediate in medicinal chemistry for constructing bioactive heterocycles.
2-Bromo-6-(methylsulfonyl)pyridine serves as a versatile building block in medicinal chemistry, enabling palladium-catalyzed cross-coupling reactions due to its well-defined electrophilic reactivity at the C2 position. The methylsulfonyl group enhances solubility and modulates electronic properties, while the bromide facilitates reliable coupling with boronic acids, stannanes, and amines under standard conditions. Its bench stability and ease of purification support efficient synthesis of complex pyridyl-containing scaffolds common in pharmaceutical development.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: