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CS-W001157 4
Total: USD 88.00

Valproic acid

  • CAS No. 99-66-1

  • Cat. No. CS-1765
  • Purity≥98%
  • MDL No.MFCD00002672

*For research and further manufacturing use only, not for direct human use.

Valproic acid|CS-1765

Structure of 99-66-1

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General Information

  • CAS No. 99-66-1
  • Cat. No. CS-1765
  • Purity ≥98%
  • MDL No. MFCD00002672
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₈H₁₆O₂
  • Molecular Weight 144.21
  • Synonym(s) Dipropylacetic Acid
  • SMILES CCCC(CCC)C(O)=O

Description

p-Terphenyl-4,4 -dithiol (TPDT) is an alkanethiol that forms a self-assembled monolayer (SAM) on a variety of substrates. It can be used to form a dithiol ligand that functionalizes and modifies the properties of surfaces.TPDT forms a SAM on gold nanoparticle by immobilizing the surface atoms, which can be used in opto-electronic and other energy based applications.

Application

Valproic acid serves as a well-established building block in medicinal chemistry, enabling the synthesis of diverse bioactive molecules through its carboxylic acid and branched alkyl functionalities. Its stability, compatibility with standard functional groups, and proven utility in forming amides, esters, and other derivatives make it a practical choice for API development and synthetic route optimization.

Synthesis

  • Route1
    • 2,2-Dipropylmalonic acid Sodium Valproate  Impurity|CS-0228865
      1636-27-7
    • ~99%
    • In-stock
      Valproic acid|CS-1765
      99-66-1

    References

    • CALYX CHEMICALS AND PHARMACEUTICALS LTD. Patent: WO2008/62471 A2, 2008 ; Location in patent: Page/Page column 10 ;
  • Route2
    • null|null
      76002-02-3
    • In-stock
      Ethyl acetoacetate|CS-0016216
      141-97-9
    • null|null
      106-94-5
    • ~%
    • In-stock
      Valproic acid|CS-1765
      99-66-1

    References

    • US5856569 A1, ;
  • Route3

    References

    • Journal of the American Chemical Society, , vol. 87, # 6 p. 1297 - 1307

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07,GHS08
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H360
Precautionary Statements : P264-P270-P280-P302+P352-P330-P362+P364-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   37.3
  • LogP   2.2874
  • H_Acceptors   1
  • H_Donors   1
  • Rotatable_Bonds   5

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