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Structure of 99-93-4
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Molecular dynamics simulation study of the two known polymorphs of 4-hydroxyacetophenone (form I, monoclinic; form II, orthorhombic) has been described.4-Hydroxyacetophenone has been used as ketone component in the preparation of 1-aryl-3-phenethylamino-1-propanone hydrochlorides, potential cytotoxic agents, via Mannich reactions.
4-Hydroxyacetophenone serves as a versatile building block in synthetic organic chemistry, enabling efficient access to bioactive heterocycles and pharmaceutical intermediates. Its dual functionality—phenolic hydroxyl and ketone group—supports diverse transformations including electrophilic substitution, enolization, and coupling reactions. The compound exhibits excellent bench stability and facilitates straightforward purification, making it well-suited for scale-up and medicinal chemistry applications.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H319-H412
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Precautionary Statements : P264-P273-P280-P501
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Lot numbers can be found on the outside label of a product: