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Structure of 99102-01-9
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This azetidinylpropanoic acid derivative features a strained four-membered azetidine ring linked to a propanoic acid chain, delivering enhanced metabolic stability and improved membrane permeability. The nitrogen-rich scaffold facilitates efficient conjugation in peptide-based drug design, while the carboxylic acid group enables direct derivatization or salt formation for optimized solubility.
3-(Azetidin-1-yl)propanoic acid serves as a versatile building block in medicinal chemistry, enabling the synthesis of bioactive molecules through its compatibility with standard amide coupling and reductive amination protocols. The azetidine moiety imparts enhanced metabolic stability and improved membrane permeability, while the carboxylic acid facilitates conjugation and derivatization. Bench-stable and readily purified by recrystallization, it functions effectively in both solution-phase and solid-phase synthesis workflows.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H312-H332
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P501
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Lot numbers can be found on the outside label of a product: