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CS-W001157 4
Total: USD 88.00

3-(Azetidin-1-yl)propanoic acid

  • CAS No. 99102-01-9

  • Cat. No. CS-W020473
  • Purity≥97%
  • MDL No.MFCD19230116

*For research and further manufacturing use only, not for direct human use.

3-(Azetidin-1-yl)propanoic acid|CS-W020473

Structure of 99102-01-9

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General Information

  • CAS No. 99102-01-9
  • Cat. No. CS-W020473
  • Purity ≥97%
  • MDL No. MFCD19230116
  • Storage 4°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₆H₁₁NO₂
  • Molecular Weight 129.16
  • Synonym(s) LITHIUM 3-(AZETIDIN-1-YL)PROPANOIC ACID
  • SMILES OC(=O)CCN1CCC1

Description

This azetidinylpropanoic acid derivative features a strained four-membered azetidine ring linked to a propanoic acid chain, delivering enhanced metabolic stability and improved membrane permeability. The nitrogen-rich scaffold facilitates efficient conjugation in peptide-based drug design, while the carboxylic acid group enables direct derivatization or salt formation for optimized solubility.

Application

3-(Azetidin-1-yl)propanoic acid serves as a versatile building block in medicinal chemistry, enabling the synthesis of bioactive molecules through its compatibility with standard amide coupling and reductive amination protocols. The azetidine moiety imparts enhanced metabolic stability and improved membrane permeability, while the carboxylic acid facilitates conjugation and derivatization. Bench-stable and readily purified by recrystallization, it functions effectively in both solution-phase and solid-phase synthesis workflows.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H312-H332
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P501

Quality Control

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Computational Chemistry Data

  • TPSA   40.54
  • LogP   0.1668
  • H_Acceptors   2
  • H_Donors   1
  • Rotatable_Bonds   3

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