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Ethyl 3-hydroxy-2-(hydroxymethyl)propanoate

  • CAS No. 99116-11-7

  • Cat. No. CS-B1343
  • Purity≥95%
  • MDL No.None
  • HazMat Fee +

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    Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

    If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

    Type
    HazMat Fee
    Excepted Quantity $0.00
    FedEx Limited Quantities Ground $0.00
    Hazmat Ground shipping $50.00+
    Inaccessible (Haz class 6.1 or 9), Domestic $68.00+
    Accessible (Haz class 3, 4, 5 or 8), Domestic $158.00+
    Inaccessible (Haz class 6.1 or 9), International $108.00+
    Accessible (Haz class 3, 4, 5 or 8), International $238.00+

    An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

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*For research and further manufacturing use only, not for direct human use.

Ethyl 3-hydroxy-2-(hydroxymethyl)propanoate|CS-B1343

Structure of 99116-11-7

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Description

Ethyl 3-hydroxy-2-(hydroxymethyl)propanoate features a bifunctional hydroxyl array and a pendant ester group, enabling straightforward derivatization in synthetic sequences. This moisture-tolerant scaffold integrates readily into complex molecular architectures under standard conditions, offering high compatibility with diverse reaction manifolds.

Application

Ethyl 3-hydroxy-2-(hydroxymethyl)propanoate serves as a versatile synthon in organic synthesis, enabling the construction of complex carbohydrate mimetics and bioactive heterocycles. Its orthogonal hydroxyl groups facilitate selective protection and functionalization, while the ester moiety supports downstream transformations such as reduction, oxidation, or coupling reactions. The molecule exhibits bench stability and is compatible with standard purification protocols, making it a practical building block for medicinal chemistry and process development workflows.

General Information

  • CAS No. 99116-11-7
  • Cat. No. CS-B1343
  • Purity ≥95%
  • MDL No. None
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₆H₁₂O₄
  • Molecular Weight 148.16
  • Synonym(s) Propanoic acid, 3-hydroxy-2-(hydroxymethyl)-, ethyl ester
  • SMILES O=C(OCC)C(CO)CO

Computational Chemistry Data

  • TPSA   66.76
  • LogP   -0.8497
  • H_Acceptors   4
  • H_Donors   2
  • Rotatable_Bonds   4

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P280-P302+P352

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