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Structure of 99451-55-5
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8-Bromo-5-(methylthio)-[1,2,4]triazolo[4,3-c]pyrimidine is a heterocyclic building block featuring a bromine substituent and a methylthio group positioned for selective functionalization. This scaffold integrates electron-deficient triazolopyrimidine core with reactive handles, enabling efficient coupling in medicinal chemistry and materials synthesis under standard conditions.
8-Bromo-5-(methylthio)-[1,2,4]triazolo[4,3-c]pyrimidine serves as a versatile building block for the synthesis of triazolopyrimidine-based scaffolds, enabling efficient functionalization at multiple sites. Its bromine and methylthio groups facilitate palladium-catalyzed cross-coupling and nucleophilic substitution reactions, offering high regioselectivity and bench stability. The compound demonstrates excellent functional group tolerance and is readily purified by crystallization, making it well-suited for iterative medicinal chemistry campaigns and process-scale applications.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: