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CS-W001157 4
Total: USD 88.00

6-Methylpiperidine-2-carboxylic acid

  • CAS No. 99571-58-1

  • Cat. No. CS-0039203
  • Purity≥95%
  • MDL No.MFCD00513436
  • HazMat Fee +

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    The shipment is processed through FedEx Ground under the Limited Quantity option.

    Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

    If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

    Type
    HazMat Fee
    Excepted Quantity $0.00
    FedEx Limited Quantities Ground $0.00
    Hazmat Ground shipping $50.00+
    Inaccessible (Haz class 6.1 or 9), Domestic $68.00+
    Accessible (Haz class 3, 4, 5 or 8), Domestic $158.00+
    Inaccessible (Haz class 6.1 or 9), International $108.00+
    Accessible (Haz class 3, 4, 5 or 8), International $238.00+

    An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

    There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

6-Methylpiperidine-2-carboxylic acid|CS-0039203

Structure of 99571-58-1

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Description

6-Methylpiperidine-2-carboxylic acid features a sterically hindered piperidine core with a methyl group at the 6-position, enhancing metabolic stability. The carboxylic acid functionality provides a polar handle for conjugation and solubility modulation. This scaffold integrates readily into bioactive molecules, offering favorable pharmacokinetic properties in medicinal chemistry applications.

Application

6-Methylpiperidine-2-carboxylic acid serves as a versatile scaffold in medicinal chemistry, enabling the construction of bioactive heterocycles through standard amide coupling and reductive amination protocols. Its tertiary amine functionality and adjacent carboxylic acid facilitate efficient derivatization, while the methyl substitution enhances metabolic stability. The compound exhibits good bench stability and compatibility with common purification methods, making it a practical building block for peptide-like libraries and targeted small-molecule synthesis.

General Information

  • CAS No. 99571-58-1
  • Cat. No. CS-0039203
  • Purity ≥95%
  • MDL No. MFCD00513436
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₇H₁₃NO₂
  • Molecular Weight 143.18
  • Synonym(s) 2-Piperidinecarboxylicacid, 6-Methyl-
  • SMILES O=C(C1NC(C)CCC1)O

Computational Chemistry Data

  • TPSA   49.33
  • LogP   0.6016
  • H_Acceptors   2
  • H_Donors   2
  • Rotatable_Bonds   1

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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