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Structure of 99571-58-1
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6-Methylpiperidine-2-carboxylic acid features a sterically hindered piperidine core with a methyl group at the 6-position, enhancing metabolic stability. The carboxylic acid functionality provides a polar handle for conjugation and solubility modulation. This scaffold integrates readily into bioactive molecules, offering favorable pharmacokinetic properties in medicinal chemistry applications.
6-Methylpiperidine-2-carboxylic acid serves as a versatile scaffold in medicinal chemistry, enabling the construction of bioactive heterocycles through standard amide coupling and reductive amination protocols. Its tertiary amine functionality and adjacent carboxylic acid facilitate efficient derivatization, while the methyl substitution enhances metabolic stability. The compound exhibits good bench stability and compatibility with common purification methods, making it a practical building block for peptide-like libraries and targeted small-molecule synthesis.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: