N-protected amino acid

N-protected amino acids refer to the introduction of a certain protecting group on the amino group (N-terminus) of the amino acid molecule in order to prevent the amino group from reacting undesirably with other reactants in chemical reactions. This protection strategy is particularly important in organic synthesis, especially in peptide synthesis, amino acid derivative synthesis, and other processes that require selective control of reactions. Commonly used N-protecting groups include Boc, Fmoc, carbamoyl, and nitrobenzyl. Different N-protecting groups can be selected according to the synthesis conditions and reaction requirements. In peptide synthesis, N-protection strategies are essential to improve synthesis efficiency, ensure selectivity, and ensure the quality of the final product.