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Cabozantinib impurity
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Cabozantinib is an orally effective VEGFR2 and MET inhibitor with IC50 of 0.035 and 1.3 nM, respectively. Cabozantinib has a strong inhibitory effect on KIT, RET, AXL, TIE2 and FLT3 (IC50=4.6, 5.2, 7, 14.3 and 11.3 nM). Cabozantinib shows anti-angiogenic activity. Cabozantinib can destroy tumor blood vessels and promote apoptosis of tumor and endothelial cells. ChemScene provides a series of Cabozantinib impurities to meet customer application needs.
Cabozantinib impurity
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