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Ibrutinib impurity
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Ibrutinib (PCI-32765) is an irreversible and selective Btk inhibitor with an IC50 value of 0.5 nM. Ibrutinib can be used as a Btk ligand to synthesize a series of PROTAC molecules, such as P13I. P13I acts on human Burkitt's lymphoma RAMOS cells, degrading 73% and 89% of Btk at concentrations of 10 and 100nM, respectively. ChemScene provides a series of Ibrutinib impurities to meet customer application requirements.
Ibrutinib impurity
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