Brexpiprazole impurity

Brexpiprazole (OPC-34712), an atypical, orally active antipsychotic, is a partial agonist at human 5-HT1A and dopamine D2L receptors with Ki values of 0.12 nM and 0.3 nM, respectively. Brexpiprazole is also an antagonist at 5-HT2A receptors with Ki of 0.47 nM. Brexpiprazole also exhibits potent antagonist activity at human noradrenergic receptors α1B (Ki=0.17 nM) and α2C (Ki=0.59 nM). ChemScene offers a range of Brexpiprazole impurities to meet customer filing requirements.