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Cat. No. Size / Unit Price Qty
CS-W001157 4
Total: USD 88.00

Doxorubicin impurity

Doxorubicin (Hydroxydaunorubicin) is a cytotoxic broad-spectrum anthracycline antibiotic commonly used as a tumor chemotherapeutic agent. Doxorubicin is fluorescent. Doxorubicin inhibits topoisomerase-II with an IC50 of 2.67 μM, thereby inhibiting DNA replication. Doxorubicin downregulates basal phosphorylation of AMPK and downstream acetyl-CoA carboxylase. Doxorubicin induces apoptosis and autophagy. Doxorubicin inhibits human DNA topoisomerase I with an IC50 of 0.8 μM. ChemScene offers a range of Doxorubicin impurities to meet customer reporting needs.

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