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CS-W001157 4
Total: USD 88.00

1H-Pyrrolo[3,2-c]pyridin-6-amine

  • CAS No. 1000342-74-4

  • Cat. No. CS-0101150
  • Molecule weight133.15
  • Purity≥95%
  • MDL No.MFCD08690136

*For research and further manufacturing use only, not for direct human use.

1H-Pyrrolo[3,2-c]pyridin-6-amine|CS-0101150

Structure of 1000342-74-4

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General Information

  • CAS No. 1000342-74-4
  • Cat. No. CS-0101150
  • Purity ≥95%
  • MDL No. MFCD08690136
  • Storage 4°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₇H₇N₃
  • Molecular Weight 133.15
  • Synonym(s) 2 1h-pyrrolo[3,2-c]pyridin-6-amine
  • SMILES NC1=CC2=C(C=N1)C=CN2

Description

1H-Pyrrolo[3,2-c]pyridin-6-amine features a fused heteroaromatic core with a strategically positioned amine group, enabling direct incorporation into diverse pharmaceutical scaffolds. This electron-rich, bench-stable scaffold supports efficient coupling reactions and serves as a key building block in targeted drug discovery programs.

Application

1H-Pyrrolo[3,2-c]pyridin-6-amine serves as a versatile heterocyclic building block in medicinal chemistry, enabling the construction of kinase inhibitors and other bioactive scaffolds. Its electron-rich pyrrolopyridine core exhibits favorable reactivity in Suzuki-Miyaura and Buchwald-Hartwig couplings, with excellent bench stability and straightforward purification. Functions as a key nitrogen-containing motif in API development due to its structural rigidity and moderate lipophilicity.

Safety Information

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GHS Pictogram :
GHS No : GHS05
Signal Word : Danger
UN#: 3261
Class : 8
Packing Group : Ⅲ
Hazard Statements : H314
Precautionary Statements : P260-P264-P280-P301+P330+P331-P303+P361+P353-P304+P340-P305+P351+P338-P363-P405-P501

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Computational Chemistry Data

  • TPSA   54.7
  • LogP   1.1451
  • H_Acceptors   2
  • H_Donors   2
  • Rotatable_Bonds   0

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