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Structure of 1011487-94-7
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(6-Chloropyridazin-3-yl)methanol features a chlorinated pyridazinone core with a reactive hydroxymethyl group, enabling direct functionalization in medicinal chemistry. This bench-stable scaffold integrates readily into bioactive molecules, offering enhanced solubility and metabolic stability in drug discovery applications.
(6-Chloropyridazin-3-yl)methanol serves as a versatile building block in medicinal chemistry, enabling efficient access to pyridazinone derivatives through nucleophilic substitution and subsequent functionalization. Its chloro group facilitates palladium-catalyzed coupling reactions, while the pendant alcohol supports derivatization via esterification or ether formation. The compound exhibits good bench stability and is compatible with standard purification protocols, making it well-suited for use in iterative synthesis campaigns targeting bioactive heterocycles.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: