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Structure of 103440-95-5
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4-Ethyl-3-nitrobenzoic acid features a conjugated aromatic core with complementary electron-withdrawing nitro and carboxylic acid groups, enabling precise tuning of reactivity in electrophilic substitution and coupling reactions. The para-ethyl substituent enhances solubility and modulates electronic effects, offering improved handling over unsubstituted analogs. This structure facilitates integration into advanced synthetic scaffolds for pharmaceutical intermediates and functional materials.
4-Ethyl-3-nitrobenzoic acid serves as a versatile building block for nitroaryl-containing heterocycles and pharmaceutical intermediates. The ortho-nitro group enables directed metalation and subsequent functionalization, while the carboxylic acid facilitates amide coupling or esterification. Bench-stable and readily purified by recrystallization, it functions effectively in standard synthetic workflows involving electrophilic substitution, reduction sequences, and transition-metal-catalyzed cross-couplings.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: