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Structure of 96-98-0
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4-Methyl-3-nitrobenzoic acid features a para-methyl group and an ortho-nitro substituent on the benzoic acid scaffold, creating a sterically hindered, electron-deficient aromatic system. This configuration enhances its utility in coupling reactions and as a building block for bioactive heterocycles. The carboxylic acid moiety enables direct derivatization under standard conditions.
4-Methyl-3-nitrobenzoic acid serves as a versatile building block in synthetic organic chemistry, enabling the construction of substituted benzoic acid derivatives and heterocyclic scaffolds. Its ortho-directing nitro group and methyl substituent offer predictable regiochemistry in electrophilic substitution and coupling reactions. The carboxylic acid functionality facilitates direct amidation, esterification, or conversion to acyl chlorides, supporting downstream derivatization in medicinal chemistry and materials science applications. Bench-stable and readily purified by recrystallization, it functions reliably in standard laboratory workflows.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: