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CS-W001157 4
Total: USD 88.00

Sumatriptan

  • CAS No. 103628-46-2

  • Cat. No. CS-0009565
  • Molecule weight295.40
  • Purity≥98%
  • MDL No.MFCD00866222

*For research and further manufacturing use only, not for direct human use.

Sumatriptan|CS-0009565

Structure of 103628-46-2

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General Information

  • CAS No. 103628-46-2
  • Cat. No. CS-0009565
  • Purity ≥98%
  • MDL No. MFCD00866222
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₄H₂₁N₃O₂S
  • Molecular Weight 295.40
  • Synonym(s) GR 43175 free base
  • SMILES O=S(CC1=CC2=C(NC=C2CCN(C)C)C=C1)(NC)=O

Application

Sumatriptan serves as a clinically validated 5-HT₁ₐ/₁ₐ receptor agonist and is widely used in the acute treatment of migraine. Its structure features a substituted indole core with a sulfonamide group, enabling robust interaction with serotonin receptors. The molecule exhibits high metabolic stability and predictable pharmacokinetics, making it a reliable scaffold for studying central nervous system pharmacology. It functions as a reference compound in migraine research and receptor binding assays.

Synthesis

  • Route1
    • 4-(Dimethylamino)butyraldehyde Dimethyl Acetal|CS-0621874
      19718-92-4
    • 1-(4-Hydrazinylphenyl)-N-methylmethanesulfonamide|CS-0732316
      139272-29-0
    • ~%
    • In-stock
      Sumatriptan|CS-0009565
      103628-46-2

    References

    • WO2004/99141 A1, ; Page 10-12 ;
  • Route2
    • null|null
      795298-24-7
    • ~%
    • In-stock
      Sumatriptan|CS-0009565
      103628-46-2

    References

    • WO2004/99141 A1, ; Page 12-14 ;
  • Route3
    • null|null
      648909-52-8
    • ~%
    • In-stock
      Sumatriptan|CS-0009565
      103628-46-2

    References

    • WO2004/99141 A1, ; Page 14-15 ;

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS08
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H361-H412
Precautionary Statements : P273-P280-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   65.2
  • LogP   1.3212
  • H_Acceptors   3
  • H_Donors   2
  • Rotatable_Bonds   6

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