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*For research and further manufacturing use only, not for direct human use.
Structure of 1040377-03-4
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This pyrazole boronate ester integrates a tetrahydropyran-4-yl group and a stable diborane moiety, enabling efficient cross-coupling under mild conditions. The protected hydroxyl functionality enhances solubility and stability in aqueous and polar organic media. Designed for direct use in Suzuki-Miyaura reactions, it delivers high yields with minimal side-product formation.
1-(Tetrahydro-2H-pyran-4-yl)-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazole serves as a stable, bench-ready boronate building block for Suzuki-Miyaura cross-coupling reactions. The tetrahydro-2H-pyran-4-yl group provides excellent solubility and protection of the alcohol functionality, while the pinacol boronate enables efficient coupling with aryl, heteroaryl, and vinyl halides under mild conditions. Its high functional group tolerance and ease of purification make it ideal for constructing complex scaffolds in medicinal chemistry and materials science applications.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: