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CS-W001157 4
Total: USD 88.00

(R)-4-ethyl-4-hydroxy-1H-pyrano[3',4':6,7]indolizino[1,2-b]quinoline-3,14(4H,12H)-dione Irinotecan Impurity

  • CAS No. 110351-92-3

  • Cat. No. CS-0164099
  • Molecule weight348.35
  • Purity≥97%
  • MDL No.MFCD18252341

*For research and further manufacturing use only, not for direct human use.

(R)-4-ethyl-4-hydroxy-1H-pyrano[3',4':6,7]indolizino[1,2-b]quinoline-3,14(4H,12H)-dione  Irinotecan Impurity|CS-0164099

Structure of 110351-92-3

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General Information

  • CAS No. 110351-92-3
  • Cat. No. CS-0164099
  • Purity ≥97%
  • MDL No. MFCD18252341
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₂₀H₁₆N₂O₄
  • Molecular Weight 348.35
  • Synonym(s) 20R-Camptothecin
  • SMILES O=C1[C@@](O)(CC)C2=C(CO1)C(N3CC4=CC5=CC=CC=C5N=C4C3=C2)=O

Synthesis

  • Route1
    • null|null
      841276-70-8
    • ~0%
    • (R)-4-ethyl-4-hydroxy-1H-pyrano[3',4':6,7]indolizino[1,2-b]quinoline-3,14(4H,12H)-dione  Irinotecan Impurity|CS-0164099
      110351-92-3
    • (S)-4-Ethyl-4-hydroxy-1H-pyrano[3',4':6,7]indolizino[1,2-b]quinoline-3,14(4H,12H)-dione Irinotecan Impurity|CS-0167146
      7689-03-4

    References

    • Zhou, Hai-Bin; Liu, Guan-Sai; Yao, Zhu-Jun Organic Letters, 2007 , vol. 9, # 10 p. 2003 - 2005
  • Route2

    References

    • Wani; Nicholas; Wall Journal of Medicinal Chemistry, 1987 , vol. 30, # 12 p. 2317 - 2319
  • Route3
    • null|null
      939055-74-0
    • ~%
    • (R)-4-ethyl-4-hydroxy-1H-pyrano[3',4':6,7]indolizino[1,2-b]quinoline-3,14(4H,12H)-dione  Irinotecan Impurity|CS-0164099
      110351-92-3

    References

    • Zhou, Hai-Bin; Liu, Guan-Sai; Yao, Zhu-Jun Organic Letters, 2007 , vol. 9, # 10 p. 2003 - 2005

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS06
Signal Word : Danger
UN#: 2811
Class : 6.1
Packing Group : Ⅲ
Hazard Statements : H301
Precautionary Statements : P264-P270-P330-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   81.42
  • LogP   2.0796
  • H_Acceptors   6
  • H_Donors   1
  • Rotatable_Bonds   1

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