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Structure of 1162257-58-0
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This boronate moiety features a trifluoromethyl-substituted pyridine scaffold, delivering enhanced electron deficiency and improved stability under standard conditions. The para-positioned trifluoromethyl group imparts strong inductive withdrawal, facilitating efficient cross-coupling reactions while maintaining bench-stable handling characteristics.
(5-(Trifluoromethyl)pyridin-2-yl)boronic acid serves as a versatile building block in Suzuki-Miyaura cross-coupling reactions, enabling efficient construction of biaryl architectures. Its trifluoromethylpyridine core imparts enhanced metabolic stability and modulated electronic properties, making it valuable for medicinal chemistry applications. The boronic acid functionality offers good bench stability, compatibility with diverse reaction conditions, and straightforward purification via aqueous workup.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: