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Structure of 1211443-58-1
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This pyrrolopyrimidine derivative features a cyclopentyl group at the 7-position and a chloro substituent at the 2-position, enhancing its lipophilicity and metabolic stability. The carboxylic acid at the 6-position enables direct conjugation or salt formation, facilitating solubility and downstream derivatization in medicinal chemistry campaigns.
2-Chloro-7-cyclopentyl-7H-pyrrolo[2,3-d]pyrimidine-6-carboxylic acid serves as a versatile building block for purine-derived heterocycles, enabling efficient access to biologically relevant scaffolds. Its functionalized pyrrolopyrimidine core facilitates late-stage diversification via nucleophilic substitution and coupling reactions. The cyclopentyl group enhances metabolic stability, while the carboxylic acid provides a handle for amide formation and derivatization. Bench-stable and compatible with standard purification methods, it functions effectively in medicinal chemistry campaigns targeting kinase inhibitors and antiviral agents.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: