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Structure of 121716-63-0
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5-Fluoro-1H-indol-6-amine is a fluorinated indole derivative featuring a primary amine at the 6-position, enabling direct conjugation in synthetic transformations. This electron-deficient scaffold integrates readily into bioactive molecule design, particularly in kinase inhibitor and CNS-targeted compound libraries. The fluorine substituent enhances metabolic stability and modulates electronic properties for improved target engagement.
5-Fluoro-1H-indol-6-amine serves as a valuable building block for the synthesis of bioactive heterocycles and pharmaceutical intermediates. Its fluorinated indole core enables enhanced metabolic stability and modulated electronic properties, while the primary amine facilitates straightforward derivatization via amidation, acylation, or coupling reactions. The compound exhibits good bench stability and is compatible with standard synthetic protocols, making it a practical choice for medicinal chemistry campaigns targeting CNS agents and kinase inhibitors.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501
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Lot numbers can be found on the outside label of a product: