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Structure of 1242320-57-5
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Methyl 5-bromo-3-hydroxypicolinate features a brominated pyridine core with strategically positioned hydroxyl and ester functionalities. This combination enables direct incorporation into diverse synthetic scaffolds, particularly in medicinal chemistry and agrochemical development. The molecule exhibits enhanced reactivity at the C5 position due to the electron-withdrawing bromo group, while the adjacent hydroxyl supports hydrogen bonding and modulates solubility. Bench-stable under standard conditions, it serves as a key intermediate for further derivatization via cross-coupling or nucleophilic substitution reactions.
Methyl 5-bromo-3-hydroxypicolinate serves as a versatile building block in synthetic medicinal chemistry, enabling direct functionalization at the 3-position via nucleophilic substitution or oxidation. The bromo group facilitates palladium-catalyzed cross-coupling reactions, while the hydroxyl moiety offers controlled derivatization potential. Bench-stable and compatible with standard purification methods, it functions effectively in the construction of bioactive heterocycles and API intermediates requiring regioselective substitution.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: