(S)-(Tetrahydrofuran-3-yl)methanol

CAS No. 124391-75-9
Cat. No. CS-0053251
Purity≥95%
MDL No.MFCD17015961

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(S)-(Tetrahydrofuran-3-yl)methanol|CS-0053251

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Description

(S)-(Tetrahydrofuran-3-yl)methanol is a chiral building block featuring a hydroxymethyl group attached to the tetrahydrofuran ring. This configuration enables stereoselective transformations in synthetic routes, particularly in medicinal chemistry and natural product synthesis. The molecule combines high stability with predictable reactivity, facilitating efficient incorporation into complex molecular architectures under standard conditions.

Application

(S)-(Tetrahydrofuran-3-yl)methanol serves as a chiral building block for synthesizing bioactive molecules, offering a rigid, stereodefined tetrahydrofuran ring with a pendant primary alcohol. Its bench-stable nature and compatibility with standard coupling and oxidation protocols enable efficient incorporation into complex intermediates. The molecule functions effectively in asymmetric synthesis, facilitating access to pharmaceutical scaffolds through predictable stereocontrol and orthogonal functionalization.

General Information

CAS No. 124391-75-9
Cat. No. CS-0053251
Purity ≥95%
MDL No. MFCD17015961
Storage 4°C
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₅H₁₀O₂
Molecular Weight 102.13
Synonym(s) (S)-Tetrahydrofuran-3-ylmethanol
SMILES OC[C@@H]1CCOC1

Computational Chemistry Data

TPSA 29.46
LogP 0.0152
H_Acceptors 2
H_Donors 1
Rotatable_Bonds 1

Safety Information

Download SDS

GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Other Classifications

Building Blocks Skeleton Aliphatic heterocycle compounds Tetrahydrofuran compounds

Building Blocks Skeleton Chiral compounds Chiral Building Blocks

Key Words

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(S)-(Tetrahydrofuran-3-yl)methanol

CAS No. 124391-75-9

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