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Structure of 90259-27-1
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2-Fluoro-6-methylbenzoic acid features a strategically positioned fluorine atom and methyl group on the aromatic ring, enabling enhanced metabolic stability and targeted electronic effects. This ortho-substituted benzoic acid serves as a key building block in medicinal chemistry, facilitating the development of bioactive compounds through its ability to modulate lipophilicity and influence binding affinity in drug candidates.
2-Fluoro-6-methylbenzoic acid serves as a valuable building block in medicinal chemistry, enabling the synthesis of bioactive heterocycles and pharmaceutical intermediates. Its ortho-fluoro and meta-methyl substituents provide enhanced metabolic stability and modulated electronic properties, facilitating direct coupling reactions and functionalization. The carboxylic acid group offers straightforward derivatization for amides, esters, and acyl chlorides, supporting diverse downstream transformations. Bench-stable and readily purified by recrystallization, it functions reliably in standard synthetic workflows.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: