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Structure of 1251011-05-8
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tert-Butyl 5-oxa-2,8-diazaspiro[3.5]nonane-2-carboxylate features a spirocyclic scaffold integrating an oxygen atom and two nitrogen centers, delivering enhanced solubility and conformational rigidity. The tert-butyl ester group enables stable storage and convenient deprotection under mild acidic conditions. This structure serves as a pivotal building block in the synthesis of complex heterocycles and bioactive molecules.
tert-Butyl 5-oxa-2,8-diazaspiro[3.5]nonane-2-carboxylate serves as a versatile spirocyclic scaffold for medicinal chemistry campaigns, enabling efficient access to constrained heterobicyclic systems. The protected amine and ester functionalities offer orthogonal reactivity, facilitating downstream derivatization via hydrogenation, nucleophilic substitution, or amide coupling. Bench-stable and readily purified by flash chromatography, it functions as a key building block in the synthesis of complex nitrogen-containing frameworks relevant to small-molecule drug discovery.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501
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Lot numbers can be found on the outside label of a product: