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CS-W001157 4
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5-Hydroxy-1-methyl-1h-pyrazole-4-carboxylic acid

  • CAS No. 1255352-25-0

  • Cat. No. CS-0300513
  • Molecule weight142.11
  • Purity≥98%
  • MDL No.MFCD21601625

*For research and further manufacturing use only, not for direct human use.

5-Hydroxy-1-methyl-1h-pyrazole-4-carboxylic acid|CS-0300513

Structure of 1255352-25-0

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General Information

  • CAS No. 1255352-25-0
  • Cat. No. CS-0300513
  • Purity ≥98%
  • MDL No. MFCD21601625
  • Storage 4°C, stored under nitrogen
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₅H₆N₂O₃
  • Molecular Weight 142.11
  • Synonym(s) None
  • SMILES CN1C(=C(C=N1)C(=O)O)O

Description

5-Hydroxy-1-methyl-1H-pyrazole-4-carboxylic acid features a polar pyrazole core with complementary hydroxyl and carboxylic acid functionalities, enabling versatile conjugation in medicinal chemistry. The electron-rich heterocycle enhances solubility and facilitates hydrogen bonding, supporting integration into bioactive scaffolds under standard conditions.

Application

5-Hydroxy-1-methyl-1H-pyrazole-4-carboxylic acid serves as a versatile heterocyclic building block for medicinal chemistry and agrochemical synthesis. Its dual functionality—phenolic hydroxyl and carboxylic acid—enables diverse derivatization via esterification, amidation, and metal-catalyzed coupling reactions. The molecule exhibits good bench stability and facilitates efficient purification, making it well-suited for iterative synthesis workflows and scaffold exploration in drug discovery programs.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

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Computational Chemistry Data

  • TPSA   75.35
  • LogP   -0.1761
  • H_Acceptors   4
  • H_Donors   2
  • Rotatable_Bonds   1

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