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Structure of 1260381-83-6
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5-Bromo-7-fluoro-1H-indazole is a heterocyclic building block featuring complementary halogen substituents at the 5 and 7 positions, enabling selective cross-coupling reactions. The electron-deficient aromatic core supports efficient metal-catalyzed transformations, while the fluorine atom enhances metabolic stability in bioactive molecule design. This compound serves as a key scaffold for medicinal chemistry and materials science applications.
5-Bromo-7-fluoro-1H-indazole serves as a versatile heterocyclic building block in medicinal chemistry, enabling palladium-catalyzed cross-coupling reactions due to its well-established reactivity at the bromine site. The fluorine substituent enhances metabolic stability and modulates electronic properties, while the indazole core provides a rigid, planar scaffold suitable for target-directed synthesis. Bench-stable and readily purified by chromatography, it functions effectively in standard coupling protocols and offers predictable regioselectivity in multi-step syntheses.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501
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Lot numbers can be found on the outside label of a product: