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7-Methyl-4,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidine

  • CAS No. 1260879-61-5

  • Cat. No. CS-0102122
  • Molecule weight137.18
  • Purity≥97%
  • MDL No.MFCD13193598

*For research and further manufacturing use only, not for direct human use.

7-Methyl-4,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidine|CS-0102122

Structure of 1260879-61-5

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General Information

  • CAS No. 1260879-61-5
  • Cat. No. CS-0102122
  • Purity ≥97%
  • MDL No. MFCD13193598
  • Storage 4°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₇H₁₁N₃
  • Molecular Weight 137.18
  • Synonym(s) 7-methyl-1,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidine
  • SMILES CC1CCNC2=CC=NN12

Description

This tetrahydropyrazolo[1,5-a]pyrimidine scaffold features a methyl group at the 7-position, conferring enhanced metabolic stability and improved solubility in polar organic solvents. The saturated ring system imparts conformational rigidity, facilitating targeted interactions in kinase inhibition studies. This core integrates readily into bioactive molecule design for CNS-targeted therapeutics.

Application

7-Methyl-4,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidine serves as a versatile heterocyclic building block in medicinal chemistry, enabling the synthesis of pyrazolopyrimidine-based scaffolds. Its well-defined reactivity profile supports functionalization at multiple positions, with excellent bench stability and compatibility with standard coupling protocols. The molecule functions effectively in transition-metal-catalyzed transformations and provides access to biologically relevant frameworks through reliable derivatization pathways.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   29.85
  • LogP   1.2597
  • H_Acceptors   3
  • H_Donors   1
  • Rotatable_Bonds   0

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