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Structure of 6968-28-1
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4-Bromophthalic acid offers a strategically positioned bromine substituent on the phthalic acid core, enabling direct functionalization in cross-coupling reactions. The carboxylic acid groups provide robust anchoring points for conjugation and metal coordination, while the electron-withdrawing bromine enhances reactivity in palladium-catalyzed transformations. This combination delivers efficient access to complex aromatic architectures under standard conditions.
4-Bromophthalic acid serves as a versatile building block in synthetic organic chemistry, enabling the construction of brominated aromatic scaffolds via standard coupling and cyclization protocols. Its dual carboxylic acid functionality provides high reactivity for amide, ester, and anhydride formation, while the ortho-bromo substituent offers a reliable handle for subsequent palladium-catalyzed cross-coupling reactions. The compound exhibits excellent bench stability and facilitates straightforward purification, making it well-suited for applications in medicinal chemistry, materials science, and the synthesis of functionalized heterocycles.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: