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Structure of 1261451-92-6
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5-Chloro-2-methoxypyridine-3-sulfonyl chloride features a reactive sulfonyl chloride group appended to a chlorinated, methoxy-substituted pyridine scaffold. This combination enables direct coupling in nucleophilic substitution reactions, facilitating rapid access to functionalized sulfonamide derivatives under mild conditions. The electron-withdrawing chlorine and methoxy groups enhance electrophilicity at the sulfonyl center while improving solubility in common organic solvents.
5-Chloro-2-methoxypyridine-3-sulfonyl chloride serves as a versatile building block for sulfonamide synthesis, enabling efficient incorporation of pyridyl sulfonamide motifs into bioactive molecules. Its reactivity profile supports straightforward coupling with amines under mild conditions, offering excellent functional group tolerance and bench stability. The molecule facilitates rapid diversification in medicinal chemistry campaigns targeting kinase inhibitors and other heterocyclic scaffolds.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501
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Lot numbers can be found on the outside label of a product: