6-Bromopyrazolo[1,5-a]pyridine

CAS No. 1264193-11-4
Cat. No. CS-W006121
Purity≥96%
MDL No.None

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6-Bromopyrazolo[1,5-a]pyridine|CS-W006121

Structure of 1264193-11-4

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Description

6-Bromopyrazolo[1,5-a]pyridine features a bromine substituent at the 6-position of a fused pyrazolo[1,5-a]pyridine core, providing a reactive handle for palladium-catalyzed cross-coupling transformations. The electron-deficient heteroaromatic framework enables efficient incorporation into bioactive scaffolds and functional materials. This bench-stable compound serves as a key intermediate in synthetic medicinal chemistry and advanced materials development.

Application

6-Bromopyrazolo[1,5-a]pyridine serves as a versatile building block for the synthesis of heterocyclic scaffolds in medicinal chemistry and catalytic cross-coupling reactions. The bromine substituent enables reliable Suzuki, Stille, or Buchwald–Hartwig coupling transformations, facilitating the construction of biaryl and complex nitrogen-containing frameworks. Its stability under standard reaction conditions and compatibility with diverse functional groups make it a practical choice for iterative synthesis and library generation.

General Information

CAS No. 1264193-11-4
Cat. No. CS-W006121
Purity ≥96%
MDL No. None
Storage Store at room temperature
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₇H₅BrN₂
Molecular Weight 197.03
Synonym(s) None
SMILES BrC1=CN2N=CC=C2C=C1

Computational Chemistry Data

TPSA 17.3
LogP 2.0968
H_Acceptors 2
H_Donors 0
Rotatable_Bonds 0

Safety Information

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GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Other Classifications

Building Blocks Skeleton Aromatic heterocycle compounds Pyridine compounds

Building Blocks Skeleton Aromatic heterocycle compounds Pyrazole compounds

Key Words

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6-Bromopyrazolo[1,5-a]pyridine

CAS No. 1264193-11-4

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