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Structure of 1287752-84-4
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4-Bromo-3-cyclopropyl-5-methyl-1H-pyrazole is a sterically defined heterocyclic scaffold featuring bromine and methyl substituents at strategic positions, enabling direct functionalization in cross-coupling reactions. The cyclopropyl group imparts conformational rigidity, while the pyrazole core offers tunable electronic properties for medicinal chemistry applications.
4-Bromo-3-cyclopropyl-5-methyl-1H-pyrazole serves as a versatile building block in medicinal chemistry, enabling palladium-catalyzed cross-coupling reactions due to its stable bromine handle. The cyclopropyl and methyl groups provide steric and electronic modulation, enhancing metabolic stability in target scaffolds. Its bench-stable solid form facilitates handling and purification, making it suitable for iterative synthesis of heterocyclic APIs and drug candidates.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302
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Precautionary Statements : P264-P270-P330-P501
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Lot numbers can be found on the outside label of a product: