Lamivudine

CAS No. 134678-17-4
Cat. No. CS-2230
Purity≥98%
MDL No.MFCD00869739

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HazMat Fee

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it. There is a HazMat shipping fee for each item that qualifies as a dangerous good, except in the following scenarios:

The shipment is processed through FedEx Ground under the Limited Quantity option.

Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

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Description

Application

Lamivudine serves as a well-established nucleoside reverse transcriptase inhibitor, featuring a cytosine analog with a stable 3'-thia modification that enhances metabolic resistance. It functions as a critical building block in antiretroviral synthesis, enabling efficient incorporation into oligonucleotide chains via standard phosphoramidite coupling protocols. The compound exhibits excellent bench stability, predictable reactivity, and high compatibility with diverse protecting group strategies, making it a reliable scaffold for the synthesis of HIV and hepatitis B therapeutics.

General Information

CAS No. 134678-17-4
Cat. No. CS-2230
Purity ≥98%
MDL No. MFCD00869739
Storage 4°C
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₈H₁₁N₃O₃S
Molecular Weight 229.26
Synonym(s) BCH-189
SMILES OC[C@H]1SC[C@@H](N2C(N=C(N)C=C2)=O)O1

Computational Chemistry Data

TPSA 90.37
LogP -0.5941
H_Acceptors 7
H_Donors 2
Rotatable_Bonds 2

Safety Information

Download SDS

GHS Pictogram :	GHS No : GHS08
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H361
Precautionary Statements : P280-P405-P501

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Other Classifications

Building Blocks Functional Group Amine

Building Blocks Skeleton Aromatic heterocycle compounds Pyrimidine compounds

Building Blocks Skeleton Aliphatic heterocycle compounds Other aliphatic heterocycles compounds

Building Blocks Skeleton Chiral compounds Chiral Building Blocks

Biochemistry Biochemicals and Reagents Nucleosides, Nucleotides, Oligonucleotides Nucleoside Analogs

Biochemistry Biochemicals and Reagents Pharmaceutical Research Reagents Antiviral Research Reagents

Biochemistry Pharmaceutical Development and Drug Discovery Research Pharmaceutical Research Reagents Antiviral Research Reagents

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Lamivudine

CAS No. 134678-17-4

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