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Structure of 137076-54-1
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Tri-tert-butyl 1,4,7,10-tetraazacyclododecane-1,4,7,10-tetraacetate (tri BOC-DOTA) can be employed as a reactant to prepare: Gadolinium ion functionalized with DOTA-LAE (lactobionic acid-ethylenediamine), which is used as a contrast agent for magnetic resonance imaging (MRI). DOTA-conjugates of ursolic acid and ZD2 peptide 64Cu-DOTA conjugates.
DOTA-tri(t-butyl ester serves as a stable, bench-ready precursor for the synthesis of radiolabeled complexes in nuclear medicine. The t-butyl esters provide enhanced solubility and stability during storage and handling, while enabling straightforward deprotection under mild acidic conditions to access the free carboxylic acid functionality. Its well-documented reactivity facilitates efficient chelation with metal ions such as lutetium-177 and yttrium-90, making it a reliable building block for targeted radiotherapeutics.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: