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CS-W001157 4
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Boc-NH-PEG1-OH

  • CAS No. 26690-80-2

  • Cat. No. CS-W007322
  • Molecule weight161.20
  • Purity≥97%
  • MDL No.MFCD00056657

*For research and further manufacturing use only, not for direct human use.

Boc-NH-PEG1-OH|CS-W007322

Structure of 26690-80-2

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General Information

  • CAS No. 26690-80-2
  • Cat. No. CS-W007322
  • Purity ≥97%
  • MDL No. MFCD00056657
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₇H₁₅NO₃
  • Molecular Weight 161.20
  • Synonym(s) N-Boc-ethanolamine
  • SMILES O=C(OC(C)(C)C)NCCO

Description

Amine protected, difunctional reagent employed in the synthesis of phosphatidyl ethanolamines and ornithine.

Application

Boc-NH-PEG1-OH serves as a versatile bifunctional building block for peptide and polymer conjugation, enabling efficient introduction of hydrophilic PEG linkers with orthogonal protection. The Boc group provides stable amine protection under standard conditions, while the terminal hydroxyl facilitates coupling reactions or further functionalization. This reagent offers excellent solubility, bench stability, and ease of purification, making it ideal for modular synthesis of bioconjugates, drug delivery systems, and surface-functionalized materials.

Synthesis

  • Route1
    • In-stock
      Di-tert-butyl dicarbonate|CS-0017817
      24424-99-5
    • null|null
      141-43-5
    • ~99%
    • In-stock
      Boc-NH-PEG1-OH|CS-W007322
      26690-80-2

    References

    • KYOWA HAKKO KOGYO CO., LTD.; Tecno Network Shikoku Co.,Ltd. Patent: EP1550651 A1, 2005 ; Location in patent: Page/Page column 32-33 ;
  • Route2

    References

    • Gopinath, Pushparathinam; Nilaya, Surapaneni; Muraleedharan, Kannoth Manheri Organic Letters, 2011 , vol. 13, # 8 p. 1932 - 1935
  • Route3
    • In-stock
      Di-tert-Butyl carbonate|CS-0146214
      34619-03-9
    • null|null
      141-43-5
    • ~%
    • In-stock
      Boc-NH-PEG1-OH|CS-W007322
      26690-80-2

    References

    • Dellaria, Joseph F.; Lindstrom, Kyle J.; Dressel, Luke T.; Duffy, Daniel E.; Heppner, Philip D.; Jacobsen, John R.; Moseman, Joan T.; Moser, William H.; Radmer, Matthew R.; Stoermer, Doris; Zimmermann, Bernhard M. Patent: US2004/10007 A1, 2004 ; Location in patent: Page 80-81 ;

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS06
Signal Word : Danger
UN#: 2810
Class : 6.1
Packing Group : Ⅲ
Hazard Statements : H301-H315-H318-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   58.56
  • LogP   0.5034
  • H_Acceptors   3
  • H_Donors   2
  • Rotatable_Bonds   2

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