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Structure of 1425485-72-8
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DBCO-C6-acid features a reactive cyclooctyne moiety linked via a six-atom aliphatic chain to a carboxylic acid group. This structure enables efficient copper-free bioconjugation while providing a handle for further derivatization or immobilization through amide bond formation. The C6 spacer offers enhanced solubility and reduced steric interference compared to shorter linkers.
DBCO-C6-acid serves as a versatile bioorthogonal building block, enabling efficient copper-free click conjugation via strain-promoted cycloaddition. The C6 linker provides optimal spacing for reduced steric hindrance, while the carboxylic acid functionality facilitates direct amide coupling or activation for further derivatization. This reagent exhibits excellent stability under physiological conditions and simplifies purification in biomolecule labeling workflows.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H315-H319-H335
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Precautionary Statements : P261-P264-P271-P280-P302+P352-P304+P340-P362+P364-P405-P501
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Lot numbers can be found on the outside label of a product: