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CS-W001157 4
Total: USD 88.00

3-Hydroxyoxetane-3-carboxylic acid

  • CAS No. 1450997-88-2

  • Cat. No. CS-0051333
  • Molecule weight118.09
  • Purity≥95%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

3-Hydroxyoxetane-3-carboxylic acid|CS-0051333

Structure of 1450997-88-2

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General Information

  • CAS No. 1450997-88-2
  • Cat. No. CS-0051333
  • Purity ≥95%
  • MDL No. None
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₄H₆O₄
  • Molecular Weight 118.09
  • Synonym(s) None
  • SMILES OC(=O)C1(O)COC1

Description

3-Hydroxyoxetane-3-carboxylic acid is a strained, oxygen-rich heterocyclic building block featuring a labile hydroxyl group and a carboxylic acid moiety. This bifunctional scaffold enables direct incorporation into bioconjugation workflows and polymer architectures under mild conditions. The oxetane ring imparts high reactivity for ring-opening transformations, while the pendant functional groups support precise derivatization in synthetic medicinal chemistry and materials science applications.

Application

3-Hydroxyoxetane-3-carboxylic acid serves as a versatile, bench-stable building block for the synthesis of bioactive heterocycles and pharmaceutical intermediates. Its oxetane ring imparts enhanced solubility and metabolic stability, while the hydroxyl and carboxylic acid groups enable straightforward derivatization via esterification, amidation, or coupling reactions. This compound functions effectively in standard peptide and small-molecule synthesis workflows, offering high functional group tolerance and predictable reactivity under mild conditions.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H315-H319-H335
Precautionary Statements : P261-P264-P271-P280-P302+P352-P304+P340-P405-P501

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Computational Chemistry Data

  • TPSA   66.76
  • LogP   -1.1677
  • H_Acceptors   3
  • H_Donors   2
  • Rotatable_Bonds   1

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