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Structure of 155310-11-5
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2,2-Difluoro-3-hydroxypropylamine features a difluoromethyl group flanking a hydroxyl-bearing carbon, delivering enhanced metabolic stability and polarity. This configuration supports targeted bioconjugation and facilitates incorporation into peptide scaffolds where solubility and resistance to enzymatic degradation are critical.
2,2-Difluoro-3-hydroxypropylamine serves as a versatile building block for fluorinated bioactive molecules, enabling efficient incorporation of difluoromethylene and hydroxyl functionalities. Its stability under standard synthetic conditions facilitates use in amide coupling, nucleophilic substitution, and heterocycle formation. The molecule functions as a key intermediate in the synthesis of fluorinated amino alcohols and peptidomimetics, offering favorable handling properties and compatibility with common protecting group strategies.
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GHS Pictogram :
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GHS No : GHS05
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Signal Word : Danger
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UN#: 3259
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Class : 8
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Packing Group : Ⅱ
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Hazard Statements : H227-H314
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Precautionary Statements : P210-P260-P264-P280-P301+P330+P331-P304+P340-P363-P370+P378-P403-P405-P501
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Lot numbers can be found on the outside label of a product: