MC-Gly-Gly-Phe

CAS No. 1599440-15-9
Cat. No. CS-0106193
Purity≥98%
MDL No.MFCD32690114

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Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

Structure of 1599440-15-9

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Description

MC-Gly-Gly-Phe delivers a stable, tripeptide scaffold with enhanced solubility and metabolic resistance. The N-terminal maleimide group enables site-specific conjugation to thiol-bearing biomolecules, while the Gly-Gly-Phe sequence provides structural flexibility and favorable pharmacokinetic properties. This combination supports efficient bioconjugation workflows in antibody-drug conjugate development and targeted delivery systems.

Application

MC-Gly-Gly-Phe serves as a well-established tripeptide building block for the synthesis of bioactive peptides and peptidomimetics. Its glycine-rich sequence enhances solubility and synthetic flexibility, while the C-terminal phenylalanine provides a robust aromatic handle for coupling reactions. The molecule exhibits excellent bench stability and facilitates efficient purification, making it ideal for use in solid-phase peptide synthesis and targeted medicinal chemistry campaigns.

General Information

CAS No. 1599440-15-9
Cat. No. CS-0106193
Purity ≥98%
MDL No. MFCD32690114
Storage 4°C
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₂₃H₂₈N₄O₇
Molecular Weight 472.49
Synonym(s) None
SMILES O=C(O)[C@H](CC1=CC=CC=C1)NC(CNC(CNC(CCCCCN2C(C=CC2=O)=O)=O)=O)=O

Computational Chemistry Data

TPSA 161.98
LogP -0.4837
H_Acceptors 6
H_Donors 4
Rotatable_Bonds 14

Safety Information

Download SDS

GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

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Other Classifications

Building Blocks Skeleton Aliphatic heterocycle compounds Pyrroline compounds

Building Blocks Skeleton Aromatic ring compounds Benzene compounds

Life Science Linker Maleimide Linkers

Life Science ADC Related Compound Cleavable Linker

Chemical Biology Pharmaceutical Development and Drug Discovery Research Reagents Antibody-Drug Conjugates (ADC) Preparation Research Reagents Cross-Linkers

Chemical Biology PEGylation PEG Oligomers

Biochemistry Biochemicals and Reagents Antibody-Drug Conjugates (ADC) Preparation Research Reagents Cross-Linkers

Biochemistry Biochemicals and Reagents Bioconjugation PEGylation Reagents and PEG Spacers

Biochemistry Pharmaceutical Development and Drug Discovery Research Antibody-Drug Conjugates (ADC) Preparation Research Reagents Cross-Linkers

Key Words

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MC-Gly-Gly-Phe

CAS No. 1599440-15-9

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