DXd

CAS No. 1599440-33-1
Cat. No. CS-0044752
Purity≥98%
MDL No.MFCD31657444

HazMat Fee +

HazMat Fee

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it. There is a HazMat shipping fee for each item that qualifies as a dangerous good, except in the following scenarios:

The shipment is processed through FedEx Ground under the Limited Quantity option.

Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

Structure of 1599440-33-1

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Description

Dxd features a robust, electron-deficient core enabling efficient coupling in cross-coupling reactions. This bench-stable reagent integrates seamlessly into synthetic workflows, delivering high functional group tolerance and predictable regioselectivity under standard conditions.

Application

Dxd serves as a robust scaffold for constructing diverse heterocyclic systems, particularly in the synthesis of biologically relevant nitrogen-containing rings. Its well-documented reactivity enables efficient cyclization under mild conditions, offering high functional group tolerance and excellent bench stability. The compound facilitates straightforward access to core frameworks used in medicinal chemistry research, with purification typically achieved via standard chromatographic methods.

General Information

CAS No. 1599440-33-1
Cat. No. CS-0044752
Purity ≥98%
MDL No. MFCD31657444
Storage 4°C
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₂₆H₂₄FN₃O₆
Molecular Weight 493.48
Synonym(s) Exatecan derivative for ADC
SMILES O=C1[C@](O)(CC)C2=C(CO1)C(N3CC4=C5C6=C(CC[C@@H]5NC(CO)=O)C(C)=C(F)C=C6N=C4C3=C2)=O

Computational Chemistry Data

TPSA 130.75
LogP 1.62292
H_Acceptors 8
H_Donors 3
Rotatable_Bonds 3

Safety Information

Download SDS

GHS Pictogram :	GHS No : GHS06,GHS09
Signal Word : Danger	UN#: 2811
Class : 6.1	Packing Group : Ⅲ
Hazard Statements : H301-H411
Precautionary Statements : P264-P270-P273-P301+P310-P330-P391-P405-P501