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Structure of 16499-57-3
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7-Fluoroquinazolin-4(3H)-one features a fluorinated quinazoline core that imparts enhanced electron-withdrawing character and metabolic stability. This scaffold integrates readily into medicinal chemistry campaigns targeting kinase inhibitors and bioactive heterocycles, offering improved binding affinity and membrane permeability under standard conditions.
7-Fluoroquinazolin-4(3H)-one serves as a versatile scaffold for medicinal chemistry and synthetic organic applications, enabling efficient construction of bioactive heterocycles. Its fluorinated aromatic core enhances metabolic stability and modulates electronic properties, while the lactam functionality offers direct handle for derivatization. The compound exhibits excellent bench stability and facilitates straightforward functionalization via nucleophilic substitution or transition-metal-catalyzed coupling reactions, making it a practical building block in API development workflows.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: