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Structure of 1677-79-8
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4-Chloropyridazin-3-ol is a bench-stable heterocyclic building block featuring a chlorine atom at the 4-position and a hydroxyl group at the 3-position. This combination imparts enhanced reactivity for nucleophilic substitution and facilitates integration into bioactive scaffolds. The electron-deficient pyridazinone core supports conjugation in pharmaceutical intermediates, enabling efficient coupling reactions under mild conditions.
4-Chloropyridazin-3-ol serves as a versatile building block in medicinal chemistry, enabling direct functionalization at the C4 position via nucleophilic substitution. Its stability under standard reaction conditions and compatibility with diverse coupling partners facilitate efficient access to substituted pyridazinones. The hydroxyl group provides a handle for derivatization, while the chloro substituent offers orthogonal reactivity, making it valuable for constructing heterocyclic scaffolds in API development.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: