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Structure of 175166-51-5
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This bicyclic oxazole scaffold features a rigid, electron-deficient core stabilized by steric shielding from the gem-dimethyl group. It integrates readily into chiral ligands and catalysts for asymmetric synthesis, offering high configurational integrity under standard bench conditions.
(3aS,3a'S,8aR,8a'R)-2,2'-(Propane-2,2-diyl)bis(8,8a-dihydro-3aH-indeno[1,2-d]oxazole) serves as a robust chiral scaffold for asymmetric synthesis, leveraging its rigid, polycyclic framework to enforce stereochemical control. The indeno[1,2-d]oxazole core exhibits excellent bench stability and functional group tolerance, enabling diverse transformations including metal-catalyzed cross-couplings and nucleophilic substitutions. Its orthogonal reactivity profile facilitates sequential derivatization in complex molecule assembly, making it a practical building block for advanced heterocyclic systems and target-oriented synthesis.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: