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CS-W001157 4
Total: USD 88.00

1-[(Triisopropylsilyl)ethynyl]-1,2-benziodoxol-3(1H)-one

  • CAS No. 181934-30-5

  • Cat. No. CS-0213613
  • Molecule weight428.38
  • Purity≥96%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

1-[(Triisopropylsilyl)ethynyl]-1,2-benziodoxol-3(1H)-one|CS-0213613

Structure of 181934-30-5

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General Information

  • CAS No. 181934-30-5
  • Cat. No. CS-0213613
  • Purity ≥96%
  • MDL No. None
  • Storage 4°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₈H₂₅IO₂Si
  • Molecular Weight 428.38
  • Synonym(s) 1-{[Tris-(1-methylethyl)silyl]ethynyl]}-1,2-benziodoxol-3(1H)-one
  • SMILES O=C1OI(C#C[Si](C(C)C)(C(C)C)C(C)C)C2=CC=CC=C12

Application

1-[(Triisopropylsilyl)ethynyl]-1,2-benziodoxol-3(1H)-one serves as a stable, bench-ready hypervalent iodine reagent enabling efficient C–C bond formation via copper-catalyzed alkyne coupling. Its triisopropylsilyl group enhances solubility and stability while facilitating straightforward deprotection. Functions reliably in Sonogashira-type reactions and heterocycle synthesis, offering predictable regioselectivity and compatibility with diverse functional groups under standard reaction conditions.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H315-H319-H335-H413
Precautionary Statements : P261-P264-P271-P273-P280-P302+P352-P304+P340-P362+P364-P405-P501

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Computational Chemistry Data

  • TPSA   26.3
  • LogP   5.0915
  • H_Acceptors   2
  • H_Donors   0
  • Rotatable_Bonds   3

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