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Structure of 188988-46-7
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tert-Butyl 3-(aminomethyl)-1H-indole-1-carboxylate features a protected amine at the indole C3 position, enabling straightforward deprotection and functionalization. The tert-butyl ester group ensures stability during handling and purification, while the pendant aminomethyl moiety facilitates conjugation or further derivatization in medicinal chemistry campaigns.
tert-Butyl 3-(aminomethyl)-1H-indole-1-carboxylate serves as a versatile building block for indole-based medicinal chemistry, enabling direct access to C3-functionalized indole scaffolds. The tert-butyl carbamate group provides excellent bench stability and ease of removal under mild acidic conditions, while the pendant primary amine facilitates downstream derivatization via amidation, alkylation, or reductive amination. Its compatibility with standard coupling protocols makes it ideal for constructing complex heterocyclic architectures in API development.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501
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Lot numbers can be found on the outside label of a product: