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Methyl 6-(chloromethyl)picolinate

  • CAS No. 220040-48-2

  • Cat. No. CS-0114083
  • Molecule weight185.61
  • Purity≥97%
  • MDL No.MFCD09951960

*For research and further manufacturing use only, not for direct human use.

Methyl 6-(chloromethyl)picolinate|CS-0114083

Structure of 220040-48-2

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General Information

  • CAS No. 220040-48-2
  • Cat. No. CS-0114083
  • Purity ≥97%
  • MDL No. MFCD09951960
  • Storage -20°C, stored under nitrogen
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₈H₈ClNO₂
  • Molecular Weight 185.61
  • Synonym(s) Methyl 6-(chloromethyl)pyridine-2-carboxylate
  • SMILES O=C(C1=NC(CCl)=CC=C1)OC

Description

Methyl 6-(chloromethyl)picolinate features a reactive chloromethyl group positioned para to the ester functionality on a picolinate scaffold. This electrophilic handle enables site-specific conjugation in synthetic and bioconjugation workflows, particularly under mild conditions. The compound exhibits robust stability under standard bench handling and integrates readily into complex molecular architectures.

Safety Information

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GHS Pictogram :
GHS No : GHS05,GHS07
Signal Word : Danger
UN#: 3261
Class : 8
Packing Group : Ⅱ
Hazard Statements : H302-H314
Precautionary Statements : P260-P264-P270-P280-P301+P330+P331-P304+P340-P330-P363-P405-P501

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Computational Chemistry Data

  • TPSA   39.19
  • LogP   1.607
  • H_Acceptors   3
  • H_Donors   0
  • Rotatable_Bonds   2

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