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Structure of 227609-85-0
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2-Fluoro-5-(hydroxymethyl)benzonitrile features a fluorinated aromatic ring paired with a strategically positioned hydroxymethyl group and nitrile functionality. This combination enables direct incorporation into synthetic sequences requiring electron-deficient arenes, stable linkages, and polar handles for further derivatization under standard conditions.
2-Fluoro-5-(hydroxymethyl)benzonitrile serves as a versatile building block in medicinal chemistry, enabling the synthesis of bioactive heterocycles and pharmaceutical intermediates. The nitrile group facilitates nucleophilic addition and cyclization reactions, while the hydroxymethyl moiety offers a handle for oxidation, protection, or derivatization. Its fluorinated aromatic core enhances metabolic stability and modulates electronic properties, making it suitable for target-directed synthesis. Bench-stable and compatible with standard purification techniques, it functions effectively in multi-step synthetic sequences.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H312-H315-H319-H332-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P405-P501
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Lot numbers can be found on the outside label of a product: